Bioinformatics: Managing Scientific Data (The Morgan Kaufmann Series in Multimedia Information and Systems)

Bioinformatics: Managing Scientific Data (The Morgan Kaufmann Series in Multimedia Information and Systems)
By Zoé Lacroix, Terence Critchlow
Publisher: Morgan Kaufmann
Number Of Pages: 300
Publication Date: 2003-07
ISBN-10 / ASIN: 155860829X
ISBN-13 / EAN: 9781558608290
Binding: Hardcover
Life science data integration and interoperability is one of the most challenging problems facing bioinformatics today. In the current age of the life sciences, investigators have to interpret many types of information from a variety of sources: lab instruments, public databases, gene expression profiles, raw sequence traces, single nucleotide polymorphisms, chemical screening data, proteomic data, putative metabolic pathway models, and many others. Unfortunately, scientists are not currently able to easily identify and access this information because of the variety of semantics, interfaces, and data formats used by the underlying data sources.
Bioinformatics: Managing Scientific Data tackles this challenge head-on by discussing the current approaches and variety of systems available to help bioinformaticians with this increasingly complex issue. The heart of the book lies in the collaboration efforts of eight distinct bioinformatics teams that describe their own unique approaches to data integration and interoperability. Each system receives its own chapter where the lead contributors provide precious insight into the specific problems being addressed by the system, why the particular architecture was chosen, and details on the system's strengths and weaknesses. In closing, the editors provide important criteria for evaluating these systems that bioinformatics professionals will find valuable.
* Provides a clear overview of the state-of-the-art in data integration and interoperability in genomics, highlighting a variety of systems and giving insight into the strengths and weaknesses of their different approaches.
* Discusses shared vocabulary, design issues, complexity of use cases, and the difficulties of transferring existing data management approaches to bioinformatics systems, which serves to connect computer and life scientists.
* Written by the primary contributors of eight reputable bioinformatics systems in academia and industry including: BioKris, TAMBIS, K2, GeneExpress, P/FDM, MBM, SDSC, SRS, and DiscoveryLink.
Summary: Great contributions, lots of details, in-depth knowledge
Rating: 5
The book compiles chapters written by different authors all of whom are experts in the area of managing life science and/or scientific data. The variety of approaches, the clear description, and the details make this book an important source for those who want to know more about the "state-of-the-art" data management in the area of bioinformatics. By presenting such a great mixtures the reader can reflect on hes/her own requirements thus using this book as a first step for making a decision how to manage one's own data in this realm.
Those who are active in managing life science data will find this book to be a great resource and a great starting point to get a comprehensive overview of alternative solutions and their strength and weaknesses.
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