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Chemical Genomics: Reviews and Protocols (Methods in Molecular Biology, Volume 3

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  • Chemical Genomics: Reviews and Protocols (Methods in Molecular Biology, Volume 310)

    Publisher: Humana Press
    Number Of Pages: 296
    Publication Date: 2005-08-01
    Sales Rank: 2781238
    ISBN / ASIN: 1588293998
    EAN: 9781588293992
    Binding: Hardcover
    Manufacturer: Humana Press
    Studio: Humana Press

    An up-to-date introduction for the uninitiated into the various "flavors" of chemical genomics with a series of readily reproducible techniques for applications in organic chemistry, protein chemistry, and computer science, emphasizing the high-throughput approaches that are the essence of chemical genomics. The techniques range from the classic design of small molecules as affinity ligands for specific protein families, to in silico docking for computational approaches to protein-small molecule interactions, to producing highly diverse collections of proteins, carbohydrates, and small molecules for use in arrays containing large numbers of these molecules. There are also methods for the production of proteins and carbohydrates using different expression systems, for analyzing proteins using mass spectrometry, and for arraying proteins and carbohydrates on solid supports. The protocols follow the successful Methods in Molecular Biology

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