The Proteasome in Neurodegeneration
Publisher: Springer
Number Of Pages: 306
Publication Date: 2006-02-07
Sales Rank: 2135896
ISBN / ASIN: 0387284990
EAN: 9780387284996
Binding: Hardcover
Manufacturer: Springer
Studio: Springer
There is increasing evidence that links together various common neurodegenerative diseases, such as Parkinson’s and Alzheimer’s diseases. Finding common themes in the pathophysiology of such disorders is increasingly important. This text addresses such a common theme—the proteasome. Since the discovery of the proteasome some 20 years ago, significant strides have been made in our understanding of proteasome biology and our understanding of the role the proteasome plays in a wide variety of biochemical events. Taken together, these studies have confirmed an important role for the proteasome in the fields of cell biology, oncology, immunology, gerontology, and neuroscience. The focus of this book is to provide an in depth analysis and provocative discussion of what role normal and aberrant proteasome function plays in regulating various aspects of brain homeostasis.
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