Tight Junctions
Tight Junctions (Molecular Biology Intelligence Unit)
Publisher: Springer
Number Of Pages: 224
Publication Date: 2006-06-09
Sales Rank: 2450308
ISBN / ASIN: 0387332014
EAN: 9780387332017
Binding: Hardcover
Manufacturer: Springer
Studio: Springer
Average Rating: 5
Tight Junctions provides a state-of-the-art view on Tight Junctions (TJs). Starting with an analysis of the evolutionary development of a transporting epithelium in early metazoans, the book describes the current TJ structure and function information, including the present day evidence supporting the presence of ion channels within TJs. Particular emphasis is given to the lessons learned from cell culture models, mutant mice and heritable human diseases. To highlight the modern vision of TJs as signaling complexes, the book discusses the establishment of TJs during development, the shuttling of TJ proteins between the plasma membrane and the nucleus, and the role of TJ proteins in cell cycle progression and cancer.
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