Hahn Lab，The Fred Hutchinson Cancer Research Center and Howard Hughes Medical Institute
Purification of oligonucleotides (which have already been purified by reverse phase) can increase the efficiency of site directed mutagenesis from around 30% to ~75% or greater in some cases.
http://www.fhcrc.org/science/labs/hahn/methods/mol_bio_meth/oligo_purification.html
