Multipotent Drosophila Intestinal Stem Cells Specify Daughter Cell Fates by Differential Notch Signaling
Benjamin Ohlstein and Allan Spradling
Science 16 February 2007: 988-992.
Stem cell daughters in the Drosophila intestine can take on one of three identities; this choice is controlled by the activation level of a common developmental receptor.
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Polymerizing Actin Fibers Position Integrins Primed to Probe for Adhesion Sites
Catherine G. Galbraith, Kenneth M. Yamada, and James A. Galbraith
Science 16 February 2007: 992-995.
In motile cells, actin fibers form integrin-covered protrusions that are poised to interact with surfaces in the cell's search for adhesion sites.
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Maplike Representation of Celestial E-Vector Orientations in the Brain of an Insect
Stanley Heinze and Uwe Homberg
Science 16 February 2007: 995-997.
The orientation of polarized light is represented as a columnar map in the locust brain, which may help to orient the insect under the open sky.
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The Calyptogena magnifica Chemoautotrophic Symbiont Genome
I. L. G. Newton, T. Woyke, T. A. Auchtung, G. F. Dilly, R. J. Dutton, M. C. Fisher, K. M. Fontanez, E. Lau, F. J. Stewart, P. M. Richardson, K. W. Barry, E. Saunders, J. C. Detter, D. Wu, J. A. Eisen, and C. M. Cavanaugh
Science 16 February 2007: 998-1000.
A chemoautotrophic symbiont of the giant clam found in hydrothermal vents has a complex metabolic repertoire and can provide its host with most nutritional needs.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
The Phosphothreonine Lyase Activity of a Bacterial Type III Effector Family
Hongtao Li, Hao Xu, Yan Zhou, Jie Zhang, Chengzu Long, Shuqin Li, She Chen, Jian-Min Zhou, and Feng Shao
Science 16 February 2007: 1000-1003.
A family of virulence factors in bacteria removes a phosphate from a key signaling enzyme in its infected host and thereby interferes with the host's innate immunity.
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Archaeal Type III RuBisCOs Function in a Pathway for AMP Metabolism
Takaaki Sato, Haruyuki Atomi, and Tadayuki Imanaka
Science 16 February 2007: 1003-1006.
In nonphotosynthetic Archaea, the enzyme RuBisCO does not fix CO2 as it does in plants; instead it salvages adenosine and diverts ribulose into the central metabolism.
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Cadherin-11 in Synovial Lining Formation and Pathology in Arthritis
David M. Lee, Hans P. Kiener, Sandeep K. Agarwal, Erika H. Noss, Gerald F. M. Watts, Osamu Chisaka, Masatoshi Takeichi, and Michael B. Brenner
Science 16 February 2007: 1006-1010.
Published online 25 January 2007 [DOI: 10.1126/science.1137306] (in Science Express Reports)
A mouse version of rheumatoid arthritis can be ameliorated by inhibition or elimination of a cell surface adhesion molecule found within joints, suggesting a therapeutic approach for humans.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
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