Science 2 February 2007: 637-639.
Upwelling of cool, nutrient-rich waters has dramatically increased in the Atlantic off Morocco, probably because preferential warming of the land has increased alongshore winds.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
Species Interactions Reverse Grassland Responses to Changing Climate
K. B. Suttle, Meredith A. Thomsen, and Mary E. Power
Science 2 February 2007: 640-642.
Changes in rainfall alter interactions among species in experimental plots of California grassland to produce overall modifications not predicted by the responses of individual species.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
An X Chromosome Gene, WTX, Is Commonly Inactivated in Wilms Tumor
Miguel N. Rivera, Woo Jae Kim, Julie Wells, David R. Driscoll, Brian W. Brannigan, Moonjoo Han, James C. Kim, Andrew P. Feinberg, William L. Gerald, Sara O. Vargas, Lynda Chin, A. John Iafrate, Daphne W. Bell, and Daniel A. Haber
Science 2 February 2007: 642-645.
Published online 4 January 2007 [DOI: 10.1126/science.1137509] (in Science Express Reports)
The identification of a gene mutated in pediatric kidney cancer suggests that genes located on the X chromosome play a greater role in cancer than has been thought.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
The DEAD-Box RNA Helicase Dbp5 Functions in Translation Termination
Thomas Gross, Anja Siepmann, Dorotheé Sturm, Merle Windgassen, John J. Scarcelli, Matthias Seedorf, Charles N. Cole, and Heike Krebber
Science 2 February 2007: 646-649.
An RNA helicase is necessary for normal termination of translation, recruiting a known termination factor into the protein complex that ends the process.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
Yeast Rtt109 Promotes Genome Stability by Acetylating Histone H3 on Lysine 56
Robert Driscoll, Amanda Hudson, and Stephen P. Jackson
Science 2 February 2007: 649-652.
A newly identified histone acetyl transferase is necessary for the stability of the genome, particularly during DNA replication.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
Rtt109 Acetylates Histone H3 Lysine 56 and Functions in DNA Replication
Junhong Han, Hui Zhou, Bruce Horazdovsky, Kangling Zhang, Rui-Ming Xu, and Zhiguo Zhang
Science 2 February 2007: 653-655.
A newly identified histone acetyl transferase is necessary for the stability of the genome, particularly during DNA replication.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
A Two-Amino Acid Change in the Hemagglutinin of the 1918 Influenza Virus Abolishes Transmission
Terrence M. Tumpey, Taronna R. Maines, Neal Van Hoeven, Laurel Glaser, Alicia Solórzano, Claudia Pappas, Nancy J. Cox, David E. Swayne, Peter Palese, Jacqueline M. Katz, and Adolfo García-Sastre
Science 2 February 2007: 655-659.
One or two changes in the amino acids of a surface protein on the 1918 influenza virus alter the sialic acid linkages sufficiently to greatly reduce transmissibility.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
Protein Kinase C ß and Prolyl Isomerase 1 Regulate Mitochondrial Effects of the Life-Span Determinant p66Shc
Paolo Pinton, Alessandro Rimessi, Saverio Marchi, Francesca Orsini, Enrica Migliaccio, Marco Giorgio, Cristina Contursi, Saverio Minucci, Fiamma Mantovani, Mariusz R. Wieckowski, Giannino Del Sal, Pier Giuseppe Pelicci, and Rosario Rizzuto
Science 2 February 2007: 659-663.
A protein that prolongs life span when mutated has oxidoreductase activity in mitochondria where it generates toxic oxygen radicals, suggesting a possible therapeutic target.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
Targeting of Diacylglycerol Degradation to M1 Muscarinic Receptors by ß-Arrestins
Christopher D. Nelson, Stephen J. Perry, Debra S. Regier, Stephen M. Prescott, Matthew K. Topham, and Robert J. Lefkowitz
Science 2 February 2007: 663-666.
A regulatory protein that limits the extent of signaling through a well-described class of receptor performs the same function for another receptor class, but by a completely different mechanism.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
Structural and Regulatory Genes Required to Make the Gas Dimethyl Sulfide in Bacteria
Jonathan D. Todd, Rachel Rogers, You Guo Li, Margaret Wexler, Philip L. Bond, Lei Sun, Andrew R. J. Curson, Gill Malin, Michael Steinke, and Andrew W. B. Johnston
Science 2 February 2007: 666-669.
A bacteria gene is found that enables cleavage of DMSP to the volatile sulfur compound dimethyl sulfide (DMS) involved in cloud nucleation and hence global warming.
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