Abstract »| Full Text »| PDF »| Supporting Online Material »|
An Inward-Facing Conformation of a Putative Metal-Chelate-Type ABC Transporter
H. W. Pinkett, A. T. Lee, P. Lum, K. P. Locher, and D. C. Rees
Science 19 January 2007: 373-377.
Published online 7 December 2006 [DOI: 10.1126/science.1133488] (in Science Express Reports)
A pump moves molecules out of cells by coupled changes in the nucleotide-binding domain and membrane-spanning helices, which switch the accessibility of the central cavity from outside to inside.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
Antibody Class Switching Mediated by Yeast Endonuclease-Generated DNA Breaks
Ali A. Zarrin, Catherine Del Vecchio, Eva Tseng, Megan Gleason, Payam Zarin, Ming Tian, and Frederick W. Alt
Science 19 January 2007: 377-381.
Published online 14 December 2006 [DOI: 10.1126/science.1136386] (in Science Express Reports)
Factors required for the DNA rearrangement that generates antibody classes can be replaced by yeast cleavage-site sequences, pointing to a general DNA repair system.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
Farmland Biodiversity and the Footprint of Agriculture
S. J. Butler, J. A. Vickery, and K. Norris
Science 19 January 2007: 381-384.
A protocol for assessing how agricultural intensification affects bird habitat and diet predicts bird population status and may be generally useful for conservation planning.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
Control of Drosophila Gastrulation by Apical Localization of Adherens Junctions and RhoGEF2
Verena Kölsch, Thomas Seher, Gregorio J. Fernandez-Ballester, Luis Serrano, and Maria Leptin
Science 19 January 2007: 384-386.
Furrow formation is initiated during gastrulation when a protein in the outer membrane of epithelial cells binds a cytoskeletal modulator, constricting the outer part of the cells.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
High-Throughput Identification of Catalytic Redox-Active Cysteine Residues
Dmitri E. Fomenko, Weibing Xing, Blakely M. Adair, David J. Thomas, and Vadim N. Gladyshev
Science 19 January 2007: 387-389.
Screening of genome databases for bound cysteine-selenocysteine pairs has identified known proteins with redox-active cysteines and predicts previously unknown ones.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
Balanced Inhibition and Excitation Drive Spike Activity in Spinal Half-Centers
Rune W. Berg, Aidas Alaburda, and Jørn Hounsgaard
Science 19 January 2007: 390-393.
The neural circuit for scratching in turtles unexpectedly shows periodic waves of simultaneous excitatory and inhibitory synaptic activity, rather than the anticipated alternating oscillations.
Abstract »| Full Text »| PDF »| Supporting Online Material »|
Wandering Minds: The Default Network and Stimulus-Independent Thought
Malia F. Mason, Michael I. Norton, John D. Van Horn, Daniel M. Wegner, Scott T. Grafton, and C. Neil Macrae
Science 19 January 2007: 393-395.
When the human brain is not engaged by outside stimulation, an active network of cortical areas apparently subserves mind-wandering.
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Technical Comments
Comment on "The Geometry of Musical Chords"
Dave Headlam and Matthew Brown
Science 19 January 2007: 330.
Abstract »| Full Text »| PDF »|
Response to Comment on "The Geometry of Musical Chords"
Dmitri Tymoczko
Science 19 January 2007: 330.
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