Volume 434 Number 7031 pp257-420
封面故事：人类X染色体完成测序
本期Nature发表了人类X染色体的详细序列，同时还发表了对女性失活的X基因的一个调查结果。女性有两个X染色体，男性有一个X染色体和一个Y染色体。为了使基因剂量相等，女性几乎使整个染色体都失去了活性。X染色体失活特征有重要临床意义，因为性染色体具有独特性质，它所包含的致病基因数量之多不成比例。现在，X和Y染色体的序列都已测定，就可以对它们从一对常染色体的演化进行详细研究。（Article, p. 325；Letter, p.396; News Feature；News and Views）。封面图片（由Alfred Pasieka 提供，来源：Science Photo Library）描绘了从该染色体中部开始（最红的部分）、并通过其臂向外移动的失活信号。
印度洋海啸预警系统
由最近发生的苏门答腊-安达曼岛地震及其海啸造成的死亡和破坏程度之大，使人们担心在相邻的巽他海沟潜没带也许会诱发另一次地震。对这一地带之上和相邻苏门答腊断层之上的应力分布所做的一个新的计算显示，在两个构造上的应力都有增加，其严重程度足以增加它们所面临的已经相当大的地震危险。这一地区发生一次大地震、同时并发另一次海啸的可能性的增加，使得在印度洋建立一个海啸预警系统的需要显得更加紧迫。
反映火星地表情况的照片
本期Nature上有三篇论文，报告了对来自搭载在欧洲航天局“火星特快”飞船上的高分辨率立体照相机的前6个月的数据所做的评估。这些图像显示了火星上存在一个低纬度冻结海洋的证据，该海洋的面积和深度与地球上的北海相似，其年龄在500万年左右。其他地表特征反映了最近的气候变化，如在低纬度地区存在雪、冰和冰川流，另外还有距今3.5亿年前的爆炸性火山喷发。
用电子计数的办法测量电流
测量电流的传统方法是，记录电流流过一个电阻后的电压降低了多少，然后根据“欧姆定律”来计算。这种方法把电流当连续流动的电荷来对待，而不是当一系列单个电子来对待。一种新的电子计数装置可以一种根本不同的方式来测量电流，即一个一个地数电子。该方法利用了一种被称为“时间相关的量子力学隧道振荡”的现象，该现象类似于更有名的“约瑟夫森效应”。电子一个一个地以精确确定的时间间隔流入一个超灵敏的电荷传感器。电子计数使得研究人员有可能准确测量极小的电流，而不会出现传统方法所有的漂动和偏移。
具有铁电和铁磁双重性能的新材料
磁铁自古代起就为人们所知了。铁电物质是80年前发现的，两种性质在技术和高等电子学的许多领域都很重要。同时具有铁电性和铁磁性的材料将把两个“母相”（parent phases）的潜在应用与一系列新应用在光学装置、电子电路和多态记忆装置等领域结合起来。这样的材料是少见的，但本期Nature上介绍的一种，即常见的“硫基尖晶石”（CdCr2S4）让人们看到了希望。该材料既有合理的成序温度（即磁性消失的温度），又有相当大的磁化和偏振，非常适合应用，而且还有巨大的磁容效应。
海床上的“囊舌虫”
“囊舌虫”（Enteropneusts）是生活在海床上的生物，它们与脊柱动物之间的关系使人们在一个世纪以前就对它们产生了浓厚兴趣。最近，来自海底的模糊图片似乎显示，“囊舌虫”有触须从其脖子部位伸出来。这一发现引起海洋生物学界很大兴趣，对了解这些被称为“Lophenteropneusts”的动物的身体构造也将有重要意义：它们是否是“囊舌虫”与其近亲、群体生活的“Pterobranchs”之间在演化上缺少的一个环节？现在，这种“Lophenteropneusts假说”已被明确证实是一个误认。一系列深海照片和录像显示，“宽脖子” “囊舌虫”在海床上滑行，研究人员用一种被称为“Slurp Gun”的装置还吸住了一只，这只新命名的虫子有“宽脖子”的外观，但这种外观不是由触须造成的。
为什么没有“人” 泡沫病毒？
科学家认为，病毒和它们的寄主必须不断相互适应才能生存。通过把灵长类的遗传演化与猿泡沫病毒的遗传演化进行比较，研究人员发现了这一给人留下深刻印象的现象。这些普遍存在的逆转录酶病毒感染所有灵长类，有趣的是人类除外。该研究表明，这些病毒已与“旧大陆”灵长类共存了至少3000万年，这使得它们成为已知最古老的脊椎动物RNA病毒。人类易感染猿泡沫病毒，与“旧大陆”的猴子有共同的演化，所以“人” 泡沫病毒的缺少会为人们的猜测提供有趣的话题。
血缘关系与人类行为
“南非综合家庭调查”收集在该国第一次民主选举于1994年4月举行之前9个月大约9000个家庭的资料。该调查的主要目的是，收集关于生活标准的资料，供决策者参考，但也要为社会学家和人类学家提供一个独特的数据库。Bowles和Dorit在对“Inclusive Fitness Models”预测人类行为的能力所进行的一项测试中完成了这项工作。来自非洲农村家庭的流动矿工寄钱给自己家里，研究人员将所观察到的汇款数额与预测的汇款数额进行比较，来判断什么是最适当利益，结果表明，流动矿工与收款人在血缘关系上的远近是预测汇款数额的因素之一。可见，血缘关系在这里是一个因素，但只是很多因素之一。
精子结构差异对生殖的影响
精子的结构是决定雄性生殖成功率的一个重要因素，所以可能承受着很大选择压力。然而，精子演化尚未受到遗传学家详细的定量研究，部分是由于首先需要收集的数据量非常大。现在，一个涉及900对斑胸草雀的繁殖实验，提供了一些必要的数字。另人吃惊的是，该实验显示，个体之间精子结构有显著差别，其中包括鞭毛和线粒体长度，二者都与精子速度密切相关。这种差异对这一物种来说可能是不常见的精子竞争的结果，也可能是母方遗传影响造成的。
分析眼睛运动的数学理论
对生存来说，几乎没有什么活动比用眼睛在附近搜索如食物、捕食者、潜在配偶、对面过来的汽车等相关目标更重要。然而，在视觉搜索过程中记录到的眼睛运动似乎经常是偶然的，甚至有人曾提出，目光方向是随机选择的。现在，一项以人为实验对象、要求他们找出一个藏在混乱背景中的目标的研究表明，视觉搜索过程远不是随机的：人眼运动非常接近用数学方法确定的最佳战略。为这项工作所开发的数学理论，可用来分析各种不同物种的搜索战略，也可能在高效自动视觉系统开发中派上用场。
血栓与肿瘤之间的直接联系
自从转移性血栓静脉炎被Trousseau在1865年诊断他自己的胰腺癌的过程中注意到以来，血栓问题经常成为隐匿性癌症（没有明显症状的癌症）的一个症侯。现在，研究人员在一个小鼠肝癌模型中发现，诱发肿瘤发育的人类致癌基因MET也调节止血基因。肝脏中MET基因已被激活的小鼠会患静脉血栓和其他血栓病，与人类隐匿性癌症和明显癌症中所看到的血栓类似。此前，在肿瘤发生与血栓形成之间没有发现直接联系。
本期目录：
Editorials
Politics versus reality p257
Japan's politicians have to face scientific uncertainty, no matter how uncomfortable it may be. They should mobilize diplomatic means, and not sacrifice scientific integrity, in their fight with North Korea.
doi: 10.1038/434257a
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Nature respects preprint servers p257
... despite false rumours to the contrary.
doi: 10.1038/434257b
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Top of pageNews
Indian regulations fail to monitor growing stem-cell use in clinics p259
India's science and health ministries are to cooperate on guidelines.
K. S. Jayaraman
doi: 10.1038/434259a
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Rugby team converts to give gene tests a try p260
Australian club wins advantage through genetically tailored training.
Carina Dennis
doi: 10.1038/434260a
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Japan plans blood-donor restrictions to combat vCJD p260
First death prompts proposal that may create blood shortage.
Ichiko Fuyuno
doi: 10.1038/434260b
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Bush settles on technical innovator to head up NASA p261
Pioneer of small, smart missions picked to run US space agency.
Tony Reichhardt
doi: 10.1038/434261a
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Global bomb-test monitor could give tsunami warnings p261
Critics fear use of politically sensitive data.
Declan Butler
doi: 10.1038/434261b
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Fallout of fertilizers set too low, studies warn p262
Greenhouse-gas levels may be seriously underestimated.
Jim Giles
doi: 10.1038/434262a
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Gene tests served up to tell fine foods from fakes p262
Japan plans to ensure local delicacies are the real thing.
Rachael Williams
doi: 10.1038/434262b
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Plans for research watchdog praised, but it may lack teeth p263
Panel to oversee British biomedical science sparks controversy.
Jim Giles
doi: 10.1038/434263a
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Row flares over attempt to dilute radioactive waste p263
Proposal for burying cold-war nuclear waste in concrete faces scrutiny.
Emma Marris
doi: 10.1038/434263b
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news in brief p264
doi: 10.1038/434264a
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Top of pageNews Features
Genetics: The X factor p266
The sequence of the 'feminine' X chromosome is a prime hunting ground for geneticists interested in the evolution of the cognitive and cultural sophistication that defines the human species. Erika Check reports.
doi: 10.1038/434266a
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Primate research: Die hard p268
Grenada's monkeys have thrived despite a huge degree of inbreeding. But now they face a new genetic bottleneck in the wake of Hurricane Ivan. Sharon Levy investigates.
doi: 10.1038/434268a
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Top of pageCorrespondence
NIH must tell whole truth about conflicts of interest p271
Little has yet been disclosed about a consulting spree that has left a legacy of harm.
Ned Feder
doi: 10.1038/434271a
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Limits to growth may be subtle but still inexorable p271
David Fisk
doi: 10.1038/434271b
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More power needed to probe cloud systems p271
T. N. Palmer
doi: 10.1038/434271c
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Top of pageBooks and Arts
Just for fun? p273
Working out why animals play is no easy task.
Bernd Heinrich reviews The Genesis of Animal Play: Testing the Limits by Gordon M. Burkhardt
doi: 10.1038/434273a
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To infinity and beyond! p274
David Lindley reviews Parallel Worlds: The Science of Alternative Universes and Our Future in the Cosmos by Michio Kaku
doi: 10.1038/434274a
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A chemical conspiracy? p275
James Clark reviews The Fluoride Deception by Christopher Bryson
doi: 10.1038/434275a
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New in paperback p275
doi: 10.1038/434275b
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Top of pagePhysics Detective
Schr?dinger's mousetrap p277
Part 9: Out in the cold.
Peter Tuthill
doi: 10.1038/434277a
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Top of pageNews and Views
Genome biology: She moves in mysterious ways p279
The human X chromosome is a study in contradictions. The detailed sequence of the X, and a survey of inactivated genes in females, help to illuminate this unique 'evolutionary space'.
Chris Gunter
doi: 10.1038/434279a
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Planetary science: Picturing a recently active Mars p280
Discoveries made with the High Resolution Stereo Camera on the Mars Express orbiter show that, as recently as a few million years ago, the surface of Mars was being shaped by flowing water, lava and ice.
Victor R. Baker
doi: 10.1038/434280a
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Evolution: Deep-sea spiral fantasies p283
Pictures of strange, gelatinous deep-sea worms have intrigued zoologists, as they hinted at the solution to an evolutionary puzzle. But does the first specimen to be obtained in good condition back the theories up?
John Gage
doi: 10.1038/434283a
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100 and 50 years ago p284
doi: 10.1038/434284a
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Applied physics: Electrons held in a queue p285
When electric currents are made sufficiently small, the electrons can be seen moving one by one. This is accomplished in a microelectronic circuit, providing a means of obtaining an accurate standard for current.
Dmitri V. Averin
doi: 10.1038/434285a
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Cancer biology: Sense out of missense p287
The p53 protein is notorious for its involvement in many cancers. Studies in mice are helping to clarify how mutations in the human p53 protein produce a wide variety of tumours.
Terry Van Dyke
doi: 10.1038/434287a
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Human genomics: Disclosure of variation p288
Now that the sequence of the human genome is almost complete, the human genomics community is turning its attention towards what, genetically speaking, makes people different.
Rasmus Nielsen
doi: 10.1038/434288a
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Language: Syntax for free? p289
Human language is based on syntax, a complex set of rules about how words can be combined. In theory, the emergence of syntactic communication might have been a comparatively straightforward process.
Ricard Solé
doi: 10.1038/434289a
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research highlights p290
doi: 10.1038/434290a
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Top of pageBrief Communications
Indonesian earthquake: Earthquake risk from co-seismic stress p291
Last year's Indonesian earthquake has increased seismic hazard in the region.
John McCloskey, Suleyman S. Nalbant and Sandy Steacy
doi: 10.1038/434291a
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Biomechanics: Independent evolution of running in vampire bats p292
Daniel K. Riskin and John W. Hermanson
doi: 10.1038/434292a
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Top of pageArtists on science: scientists on art
Editorial p293
Alison Abbott and Adam Rutherford
doi: 10.1038/434293a
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Fiction informed by science p294
A. S. Byatt's encounters with science shape the story and characters in her four-part series of novels.
doi: 10.1038/434294a
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Science in literature p297
Simon Mawer crosses the divide to explore how scientists and novelists alike grapple with an uncertain world.
doi: 10.1038/434297a
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A tale of two loves p299
The arts and sciences provide complementary ways of looking at the world, argues Alan Lightman.
doi: 10.1038/434299a
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The artist as neuroscientist p301
Artistic licence taps into the simplified physics used by our brain to recognize everyday scenes, says Patrick Cavanagh.
Patrick Cavanagh
doi: 10.1038/434301a
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From science in art to the art of science p308
Shared intuitions about the natural world drive the pursuits of artists and scientists, says Martin Kemp.
Martin Kemp
doi: 10.1038/434308a
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Experimental physics, experimental art p310
What happens when artists and particle physicists are brought together to exchange ideas? Ken McMullen describes the creative fallout.
Ken McMullen
doi: 10.1038/434310a
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Music, the food of neuroscience? p312
Playing, listening to and creating music involves practically every cognitive function. Robert Zatorre explains how music can teach us about speech, brain plasticity and even the origins of emotion.
Robert Zatorre
doi: 10.1038/434312a
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The evolution of sensibility p316
Understanding the science behind aesthetic perception could guide and restrain the 'shock of the new' approach to music. Composer Roger Reynolds explains how.
Composer Roger Reynolds
doi: 10.1038/434316a
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Poetry and science: greatness in little p320
Peter Forbes explores how poetry and science can mutually inspire.
Peter Forbes
doi: 10.1038/434320a
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Top of pageArticles
The DNA sequence of the human X chromosome p325
Mark T. Ross, Darren V. Grafham, Alison J. Coffey, Steven Scherer, Kirsten McLay, Donna Muzny, Matthias Platzer, Gareth R. Howell, Christine Burrows, Christine P. Bird, Adam Frankish, Frances L. Lovell, Kevin L. Howe, Jennifer L. Ashurst, Robert S. Fulton, Ralf Sudbrak, Gaiping Wen, Matthew C. Jones, Matthew E. Hurles, T. Daniel Andrews, Carol E. Scott, Stephen Searle, Juliane Ramser, Adam Whittaker, Rebecca Deadman, Nigel P. Carter, Sarah E. Hunt, Rui Chen, Andrew Cree, Preethi Gunaratne, Paul Havlak, Anne Hodgson, Michael L. Metzker, Stephen Richards, Graham Scott, David Steffen, Erica Sodergren, David A. Wheeler, Kim C. Worley, Rachael Ainscough, Kerrie D. Ambrose, M. Ali Ansari-Lari, Swaroop Aradhya, Robert I. S. Ashwell, Anne K. Babbage, Claire L. Bagguley, Andrea Ballabio, Ruby Banerjee, Gary E. Barker, Karen F. Barlow, Ian P. Barrett, Karen N. Bates, David M. Beare, Helen Beasley, Oliver Beasley, Alfred Beck, Graeme Bethel, Karin Blechschmidt, Nicola Brady, Sarah Bray-Allen, Anne M. Bridgeman, Andrew J. Brown, Mary J. Brown, David Bonnin, Elspeth A. Bruford, Christian Buhay, Paula Burch, Deborah Burford, Joanne Burgess, Wayne Burrill, John Burton, Jackie M. Bye, Carol Carder, Laura Carrel, Joseph Chako, Joanne C. Chapman, Dean Chavez, Ellson Chen, Guan Chen, Yuan Chen, Zhijian Chen, Craig Chinault, Alfredo Ciccodicola, Sue Y. Clark, Graham Clarke, Chris M. Clee, Sheila Clegg, Kerstin Clerc-Blankenburg, Karen Clifford, Vicky Cobley, Charlotte G. Cole, Jen S. Conquer, Nicole Corby, Richard E. Connor, Robert David, Joy Davies, Clay Davis, John Davis, Oliver Delgado, Denise DeShazo, Pawandeep Dhami, Yan Ding, Huyen Dinh, Steve Dodsworth, Heather Draper, Shannon Dugan-Rocha, Andrew Dunham, Matthew Dunn, K. James Durbin, Ireena Dutta, Tamsin Eades, Matthew Ellwood, Alexandra Emery-Cohen, Helen Errington, Kathryn L. Evans, Louisa Faulkner, Fiona Francis, John Frankland, Audrey E. Fraser, Petra Galgoczy, James Gilbert, Rachel Gill, Gernot Gl?ckner, Simon G. Gregory, Susan Gribble, Coline Griffiths, Russell Grocock, Yanghong Gu, Rhian Gwilliam, Cerissa Hamilton, Elizabeth A. Hart, Alicia Hawes, Paul D. Heath, Katja Heitmann, Steffen Hennig, Judith Hernandez, Bernd Hinzmann, Sarah Ho, Michael Hoffs, Phillip J. Howden, Elizabeth J. Huckle, Jennifer Hume, Paul J. Hunt, Adrienne R. Hunt, Judith Isherwood, Leni Jacob, David Johnson, Sally Jones, Pieter J. de Jong, Shirin S. Joseph, Stephen Keenan, Susan Kelly, Joanne K. Kershaw, Ziad Khan, Petra Kioschis, Sven Klages, Andrew J. Knights, Anna Kosiura, Christie Kovar-Smith, Gavin K. Laird, Cordelia Langford, Stephanie Lawlor, Margaret Leversha, Lora Lewis, Wen Liu, Christine Lloyd, David M. Lloyd, Hermela Loulseged, Jane E. Loveland, Jamieson D. Lovell, Ryan Lozado, Jing Lu, Rachael Lyne, Jie Ma, Manjula Maheshwari, Lucy H. Matthews, Jennifer McDowall, Stuart McLaren, Amanda McMurray, Patrick Meidl, Thomas Meitinger, Sarah Milne, George Miner, Shailesh L. Mistry, Margaret Morgan, Sidney Morris, Ines Müller, James C. Mullikin, Ngoc Nguyen, Gabriele Nordsiek, Gerald Nyakatura, Christopher N. O'Dell, Geoffery Okwuonu, Sophie Palmer, Richard Pandian, David Parker, Julia Parrish, Shiran Pasternak, Dina Patel, Alex V. Pearce, Danita M. Pearson, Sarah E. Pelan, Lesette Perez, Keith M. Porter, Yvonne Ramsey, Kathrin Reichwald, Susan Rhodes, Kerry A. Ridler, David Schlessinger, Mary G. Schueler, Harminder K. Sehra, Charles Shaw-Smith, Hua Shen, Elizabeth M. Sheridan, Ratna Shownkeen, Carl D. Skuce, Michelle L. Smith, Elizabeth C. Sotheran, Helen E. Steingruber, Charles A. Steward, Roy Storey, R. Mark Swann, David Swarbreck, Paul E. Tabor, Stefan Taudien, Tineace Taylor, Brian Teague, Karen Thomas, Andrea Thorpe, Kirsten Timms, Alan Tracey, Steve Trevanion, Anthony C. Tromans, Michele d'Urso, Daniel Verduzco, Donna Villasana, Lenee Waldron, Melanie Wall, Qiaoyan Wang, James Warren, Georgina L. Warry, Xuehong Wei, Anthony West, Siobhan L. Whitehead, Mathew N. Whiteley, Jane E. Wilkinson, David L. Willey, Gabrielle Williams, Leanne Williams, Angela Williamson, Helen Williamson, Laurens Wilming, Rebecca L. Woodmansey, Paul W. Wray, Jennifer Yen, Jingkun Zhang, Jianling Zhou, Huda Zoghbi, Sara Zorilla, David Buck, Richard Reinhardt, Annemarie Poustka, André Rosenthal, Hans Lehrach, Alfons Meindl, Patrick J. Minx, LaDeana W. Hillier, Huntington F. Willard, Richard K. Wilson, Robert H. Waterston, Catherine M. Rice, Mark Vaudin, Alan Coulson, David L. Nelson, George Weinstock, John E. Sulston, Richard Durbin, Tim Hubbard, Richard A. Gibbs, Stephan Beck, Jane Rogers and David R. Bentley
doi: 10.1038/nature03440
Abstract | Full Text | PDF (515K) | Supplementary information
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Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals p338
Xiaohui Xie, Jun Lu, E. J. Kulbokas, Todd R. Golub, Vamsi Mootha, Kerstin Lindblad-Toh, Eric S. Lander and Manolis Kellis
doi: 10.1038/nature03441
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Tropical to mid-latitude snow and ice accumulation, flow and glaciation on Mars p346
J. W. Head, G. Neukum, R. Jaumann, H. Hiesinger, E. Hauber, M. Carr, P. Masson, B. Foing, H. Hoffmann, M. Kreslavsky, S. Werner, S. Milkovich, S. van Gasselt and The HRSC Co-Investigator Team
doi: 10.1038/nature03359
Abstract | Full Text | PDF (329K)
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Top of pageLetters to Nature
Evidence from the Mars Express High Resolution Stereo Camera for a frozen sea close to Mars' equator p352
John B. Murray, Jan-Peter Muller, Gerhard Neukum, Stephanie C. Werner, Stephan van Gasselt, Ernst Hauber, Wojciech J. Markiewicz, James W. Head, III, Bernard H. Foing, David Page, Karl L. Mitchell, Ganna Portyankina and The HRSC Co-Investigator Team
doi: 10.1038/nature03379
First paragraph | Full Text | PDF (360K)
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Discovery of a flank caldera and very young glacial activity at Hecates Tholus, Mars p356
Ernst Hauber, Stephan van Gasselt, Boris Ivanov, Stephanie Werner, James W. Head, Gerhard Neukum, Ralf Jaumann, Ronald Greeley, Karl L. Mitchell, Peter Muller and The HRSC Co-Investigator Team
doi: 10.1038/nature03423
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Current measurement by real-time counting of single electrons p361
Jonas Bylander, Tim Duty and Per Delsing
doi: 10.1038/nature03375
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Relaxor ferroelectricity and colossal magnetocapacitive coupling in ferromagnetic CdCr2S4 p364
J. Hemberger, P. Lunkenheimer, R. Fichtl, H.-A. Krug von Nidda, V. Tsurkan and A. Loidl
doi: 10.1038/nature03348
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Two-electron dissociation of single molecules by atomic manipulation at room temperature p367
P. A. Sloan and R. E. Palmer
doi: 10.1038/nature03385
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Subducted banded iron formations as a source of ultralow-velocity zones at the core?mantle boundary p371
David P. Dobson and John P. Brodholt
doi: 10.1038/nature03430
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'Lophenteropneust' hypothesis refuted by collection and photos of new deep-sea hemichordates p374
Nicholas D. Holland, David A. Clague, Dennis P. Gordon, Andrey Gebruk, David L. Pawson and Michael Vecchione
doi: 10.1038/nature03382
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Ancient co-speciation of simian foamy viruses and primates p376
William M. Switzer, Marco Salemi, Vedapuri Shanmugam, Feng Gao, Mian-er Cong, Carla Kuiken, Vinod Bhullar, Brigitte E. Beer, Dominique Vallet, Annie Gautier-Hion, Zena Tooze, Francois Villinger, Edward C. Holmes and Walid Heneine
doi: 10.1038/nature03341
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Genetic relatedness predicts South African migrant workers' remittances to their families p380
S. Bowles and D. Posel
doi: 10.1038/nature03420
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Genetic effects on sperm design in the zebra finch p383
T. R. Birkhead, E. J. Pellatt, P. Brekke, R. Yeates and H. Castillo-Juarez
doi: 10.1038/nature03374
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Optimal eye movement strategies in visual search p387
Jiri Najemnik and Wilson S. Geisler
doi: 10.1038/nature03390
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The first cleavage of the mouse zygote predicts the blastocyst axis p391
Berenika Plusa, Anna-Katerina Hadjantonakis, Dionne Gray, Karolina Piotrowska-Nitsche, Agnieszka Jedrusik, Virginia E. Papaioannou, David M. Glover and Magdalena Zernicka-Goetz
doi: 10.1038/nature03388
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The MET oncogene drives a genetic programme linking cancer to haemostasis p396
Carla Boccaccio, Gabriella Sabatino, Enzo Medico, Flavia Girolami, Antonia Follenzi, Gigliola Reato, Antonino Sottile, Luigi Naldini and Paolo M. Comoglio
doi: 10.1038/nature03357
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X-inactivation profile reveals extensive variability in X-linked gene expression in females p400
Laura Carrel and Huntington F. Willard
doi: 10.1038/nature03479
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The vacuolar Ca2+-activated channel TPC1 regulates germination and stomatal movement p404
Edgar Peiter, Frans J. M. Maathuis, Lewis N. Mills, Heather Knight, Jér?me Pelloux, Alistair M. Hetherington and Dale Sanders
doi: 10.1038/nature03381
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Molecular determinants and guided evolution of species-specific RNA editing p409
Robert A. Reenan
doi: 10.1038/nature03364
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Erratum : Pleistocene to Holocene extinction dynamics in giant deer and woolly mammoth p413
A. J. Stuart, P. A. Kosintsev, T. F. G. Higham and A. M. Lister
doi: 10.1038/nature03413
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Top of pageNaturejobs
Prospects
Postdocs, mentor thyselves p415
Paul Smaglik
doi: 10.1038/nj7031-415a
Full Text | PDF (126K)
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Postdocs
Make your point p416
Engaging presentations can land jobs and increase visibility. Kendall Powell learns the art of a good talk.
Kendall Powell
doi: 10.1038/nj7031-416a
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Career View
Graduate Journal: Writer's block p418
Anne Margaret Lee
doi: 10.1038/nj7031-418a
Full Text | PDF (70K)
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Scientists & Societies p418
Michael Strong
doi: 10.1038/nj7031-418b
Full Text | PDF (70K)
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Movers p418
doi: 10.1038/nj7031-418c
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Top of pageFutures
Last man standing p420
Whatever happened to 'boy meets girl'?
Xaviera Young
doi: 10.1038/434420a
Full Text | PDF (255K)
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